中国呼吸与危重监护杂志

中国呼吸与危重监护杂志

我国城区门诊支气管哮喘患者疾病严重程度及合并症的调查分析

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目的 调查我国城区门诊支气管哮喘患者疾病严重程度及合并症。 方法 2015 年 10 月至 2016 年 5 月于我国内地(除西藏外)30 个省、自治区、直辖市的 30 家三级甲等医院进行面对面问卷调查研究,符合入选标准的门诊哮喘患者纳入研究。研究内容包括:(1)一般资料;(2)吸烟状态;(3)疾病严重程度;(4)合并症。 结果 本次调查共纳入 3 875 例门诊哮喘患者。根据 GINA 指南,疾病严重程度分级:间歇状态 52.5%(2 033/3 875),轻度持续 24.5%(951/3 875),中度持续 16.9%(656/3 875),重度持续 6.1%(235/3 875)。体重超重率 32.9%(1 274/3 875),肥胖率 10.3%(401/3 875);吸烟率为 20.1%(777/3 875),其中现行吸烟率为 7.7%(298/3 875)。肥胖、吸烟均与哮喘控制不佳相关。75.9%(2 941/3 875)的哮喘患者有合并症,依次为:过敏性鼻炎 43.4%(1 682/3 875),高血压病 16.4%(634/3 875),鼻窦炎 8.7%(338/3 875),慢性阻塞性肺疾病 7.3%(283/3 875),支气管扩张症 3.0%(118/3 875),鼻息肉 2.9%(114/3 875)。 结论 门诊就诊的哮喘患者轻度占多数。哮喘患者共患过敏性鼻炎、支气管扩张的比例显著高于人群平均水平。肥胖、吸烟均与哮喘控制不佳相关。

Objective To investigate the disease severity and comorbidities in outpatient with asthma from urban area in China. Methods A face-to-face, questionnaire-based survey was carried out in outpatient department in 30 general hospitals from 30 provinces in China mainland except for Tibet during October 2015 to May 2016, and asthma patients who meet the including criteria were enrolled. Data of demographic characteristics, smoking status, disease severity, and comorbidities were collected. Results A total of 3 875 cases were included. According to GINA criteria, the proportion of diseases severity was as following: intermittent status 52.5% (2 033/3 875), mild persistent 24.5% (951/3 875), moderate persistent 16.9% (656/3 875), and severe persistent 6.1% (235/3 875). The overweight rate was 32.9% (1 274/3 875), the rate of obesity was 10.3% (401/3 875), and the smoking rate was 20.1% (777/3 875). Obesity and smoking were related to poor asthma control. 75.9% (2 941/3 875) of the patients had comorbidities: allergic rhinitis 43.4% (1682/3 875), hypertension 16.4% (634/3 875), nasosinusitis 8.7% (338/3 875), chronic obstructive pulmonary disease 7.3% (283/3 875), bronchiectasis 3.0% (118/3 875), and rhinopolypus 2.9% (114/3 875). Conclusions The majority of asthma patients from outpatient department are mild asthma patients. The proportion of allergic rhinitis and bronchiectasis in asthma patients is higher than mean level. Asthma patients with comorbidities of obesity and smoking is related to poor asthma control.

关键词: 哮喘; 横断面研究; 问卷调查; 合并症; 疾病严重程度

Key words: Asthma; Cross-sectional studies; Questionnaire-based survey; Comorbidities; Disease severity

引用本文: 王文巧, 林江涛, 刘春涛, 周新, 王长征, 黄茂, 蔡绍曦, 陈萍, 林其昌, 周建英, 顾玉海, 袁雅冬, 孙德俊, 杨晓红, 杨岚, 霍建民, 陈卓昌, 蒋萍, 张捷, 叶贤伟, 刘辉国, 唐华平, 刘荣玉, 张伟, 胡成平, 陈一强, 刘晓菊, 戴路明, 周玮, 黄奕江, 许建英. 我国城区门诊支气管哮喘患者疾病严重程度及合并症的调查分析. 中国呼吸与危重监护杂志, 2019, 18(1): 51-56. doi: 10.7507/1671-6205.201807058 复制

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